More Stem Cell Background
Dr. John Bertrand Gurdon, professor of developmental biology at Cambridge University, shared the Nobel Prize in Physiology or Medicine, 2012, for his pioneering work in stem cells. Dr. Gurdon, who earned his PhD in developmental biology from Oxford University, and later was trained in molecular biology during his postdoctoral fellowship at the California Institute of Technology, culminated this combined training into his studies that led to the discovery of how normal mature cells can be reprogrammed to become pluripotent, i.e. become stem cells. Dr. Greg Maguire, while a postdoctoral fellow at the University of California, Berkeley, and at Cold Spring Harbor Labs in New York, learned from Dr. Gurdon the techniques of nuclear transfer, and the translation of microinjected messenger RNA molecules in oocytes as a means to analyze DNA to RNA to protein synthesis. Dr. Gurdon’s teaching of his pioneering work, for which he was awarded the Nobel Prize, were very important in the eventual development of S²RM® technology developed by Maguire and his colleague Peter Friedman.